CMap Candidate Details

Structure:
CMap ID: C22185
Pert ID: BRD-K62206109
Compound Name: VUF-5681
Targets: HRH3
MoA: Histamine receptor antagonist
SMILES: C(CC1CCNCC1)Cc2c[nH]cn2
InchiKey: YPGRNKJNOSUCLY-UHFFFAOYSA-N
Compound Aliases: --

Score ID Pert ID Cell Line Pert Dose Pert Time Raw Score (GSE126848) Normalized Score (GSE126848) fdr_q_nlog10 (GSE126848) Raw Score (GSE135251) Normalized Score (GSE135251) fdr_q_nlog10 (GSE135251)
1763 BRD-K62206109 HA1E 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
2108 BRD-K62206109 HCC515 10 uM 6 h -0.25 -1.05 0.23 0.0 0.0 0.0
2233 BRD-K62206109 PC3 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
2550 BRD-K62206109 VCAP 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
41959 BRD-K62206109 A549 10 uM 24 h -0.18 -0.76 0.0 -0.31 -1.04 0.68
42418 BRD-K62206109 ASC 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
42734 BRD-K62206109 HEPG2 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
43035 BRD-K62206109 HT29 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
43338 BRD-K62206109 MCF??7.00 10 uM 6 h 0.22 0.91 0.03 0.4 1.42 2.2
43600 BRD-K62206109 NPC 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
43903 BRD-K62206109 PHH 10 uM 24 h 0.0 0.0 0.0 0.34 1.22 1.15
44160 BRD-K62206109 SKB 10 uM 24 h 0.0 0.0 0.0 -0.32 -1.07 0.76
99301 BRD-K62206109 U2OS 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).