CMap Candidate Details

Structure:
CMap ID: C02222
Pert ID: BRD-A92177080
Compound Name: betamethasone-acetate
Targets: NR3C1
MoA: Glucocorticoid receptor agonist
SMILES: C[C@H]1CC2C3CCC4=CC(=O)C=C[C@]4(C)[C@@]3(F)[C@@H](O)C[C@]2(C)[C@@]1(O)C(=O)COC(C)=O
InchiKey: AKUJBENLRBOFTD-DKNQJTFPSA-N
Compound Aliases: --

Score ID Pert ID Cell Line Pert Dose Pert Time Raw Score (GSE126848) Normalized Score (GSE126848) fdr_q_nlog10 (GSE126848) Raw Score (GSE135251) Normalized Score (GSE135251) fdr_q_nlog10 (GSE135251)
5289 BRD-A92177080 HA1E 10 uM 24 h 0.0 0.0 0.0 -0.34 -1.15 1.07
5744 BRD-A92177080 HCC515 10 uM 6 h 0.0 0.0 0.0 -0.3 -1.02 0.61
5996 BRD-A92177080 HT29 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
6155 BRD-A92177080 PC3 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
6424 BRD-A92177080 VCAP 10 uM 24 h 0.0 0.0 0.0 -0.4 -1.34 1.85
37110 BRD-A92177080 A375 10 uM 6 h 0.0 0.0 0.0 -0.38 -1.27 1.39
37259 BRD-A92177080 A549 10 uM 24 h 0.0 0.0 0.0 -0.22 -0.73 0.04
37565 BRD-A92177080 ASC 10 uM 24 h 0.0 0.0 0.0 -0.31 -1.05 0.69
37862 BRD-A92177080 HEPG2 10 uM 6 h 0.0 0.0 0.0 0.33 1.17 0.95
38172 BRD-A92177080 MCF??7.00 10 uM 24 h 0.0 0.0 0.0 -0.22 -0.74 0.05
38405 BRD-A92177080 NPC 10 uM 24 h 0.0 0.0 0.0 -0.2 -0.68 0.02
38896 BRD-A92177080 SKB 10 uM 24 h 0.0 0.0 0.0 0.31 1.09 0.67
The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).