CMap Candidate Details

Structure:
CMap ID: C22240
Pert ID: BRD-K62363391
Compound Name: dapsone
Targets: DHFR
MoA: Bacterial antifolate
SMILES: Nc1ccc(cc1)S(=O)(=O)c1ccc(N)cc1
InchiKey: MQJKPEGWNLWLTK-UHFFFAOYSA-N
Compound Aliases: --

Score ID Pert ID Cell Line Pert Dose Pert Time Raw Score (GSE126848) Normalized Score (GSE126848) fdr_q_nlog10 (GSE126848) Raw Score (GSE135251) Normalized Score (GSE135251) fdr_q_nlog10 (GSE135251)
50388 BRD-K62363391 HCC515 10 uM 6 h -0.17 -0.72 0.0 0.0 0.0 0.0
51048 BRD-K62363391 VCAP 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
96525 BRD-K62363391 PC3 1.11 uM 24 h -0.17 -0.7 0.0 0.31 1.1 0.7
99308 BRD-K62363391 U2OS 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
124654 BRD-K62363391 HELA 10 uM 24 h 0.0 0.0 0.0 -0.33 -1.1 0.87
124686 BRD-K62363391 HT29 1.11 uM 24 h 0.0 0.0 0.0 -0.28 -0.95 0.41
124789 BRD-K62363391 MDAMB231 0.04 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
132659 BRD-K62363391 A375 2.22 uM 24 h 0.0 0.0 0.0 0.37 1.3 1.49
132684 BRD-K62363391 A549 0.74 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
132717 BRD-K62363391 HA1E 2.22 uM 24 h 0.0 0.0 0.0 -0.32 -1.07 0.75
132746 BRD-K62363391 HEK293 0.03 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
132829 BRD-K62363391 JURKAT 0.03 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
132864 BRD-K62363391 MCF10A 0.25 uM 24 h -0.25 -1.04 0.21 0.0 0.0 0.0
132896 BRD-K62363391 MCF??7.00 0.25 uM 24 h 0.21 0.89 0.02 0.35 1.25 1.29
132929 BRD-K62363391 THP1 0.08 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
132947 BRD-K62363391 YAPC 0.03 uM 24 h 0.0 0.0 0.0 0.27 0.94 0.29
The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).