CMap Candidate Details

Structure:
CMap ID: C02229
Pert ID: BRD-A92585442
Compound Name: RU-28318
Targets: NR3C2
MoA: Cytochrome P450 inhibitor
SMILES: CCCC1CC2=CC(=O)CCC2(C)C3CCC4(C)C(CCC4(O)CCC(=O)O)C13
InchiKey: DNHCHRGCTVRAFT-UHFFFAOYSA-N
Compound Aliases: --

Score ID Pert ID Cell Line Pert Dose Pert Time Raw Score (GSE126848) Normalized Score (GSE126848) fdr_q_nlog10 (GSE126848) Raw Score (GSE135251) Normalized Score (GSE135251) fdr_q_nlog10 (GSE135251)
6712 BRD-A92585442 A375 10 uM 24 h 0.0 0.0 0.0 -0.27 -0.91 0.3
7127 BRD-A92585442 A549 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
7281 BRD-A92585442 HA1E 10 uM 24 h 0.0 0.0 0.0 -0.4 -1.34 1.85
7610 BRD-A92585442 HCC515 10 uM 6 h -0.3 -1.24 0.67 -0.31 -1.05 0.7
7823 BRD-A92585442 HT29 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
8071 BRD-A92585442 MCF??7.00 10 uM 24 h 0.0 0.0 0.0 -0.21 -0.72 0.04
8487 BRD-A92585442 PC3 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
8637 BRD-A92585442 VCAP 10 uM 24 h 0.0 0.0 0.0 -0.25 -0.85 0.2
The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).