CMap Candidate Details

Structure:
CMap ID: C22301
Pert ID: BRD-K62562723
Compound Name: SR-2640
Targets: CYSLTR1
MoA: Leukotriene receptor antagonist
SMILES: OC(=O)c1ccccc1Nc1cccc(OCc2ccc3ccccc3n2)c1
InchiKey: LMPZHLXYBWGGNT-UHFFFAOYSA-N
Compound Aliases: --

Score ID Pert ID Cell Line Pert Dose Pert Time Raw Score (GSE126848) Normalized Score (GSE126848) fdr_q_nlog10 (GSE126848) Raw Score (GSE135251) Normalized Score (GSE135251) fdr_q_nlog10 (GSE135251)
99311 BRD-K62562723 U2OS 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
124932 BRD-K62562723 A375 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
124992 BRD-K62562723 HA1E 10 uM 24 h 0.19 0.81 0.0 0.0 0.0 0.0
125094 BRD-K62562723 MCF??7.00 10 uM 24 h 0.0 0.0 0.0 -0.3 -1.01 0.56
125104 BRD-K62562723 MDAMB231 10 uM 24 h 0.0 0.0 0.0 -0.33 -1.1 0.88
125130 BRD-K62562723 PC3 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
125151 BRD-K62562723 THP1 10 uM 24 h 0.0 0.0 0.0 0.32 1.13 0.84
125200 BRD-K62562723 YAPC 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
132992 BRD-K62562723 A549 2.22 uM 24 h 0.0 0.0 0.0 -0.22 -0.73 0.05
133037 BRD-K62562723 HEK293 2.22 uM 24 h -0.25 -1.05 0.23 0.0 0.0 0.0
133085 BRD-K62562723 HELA 2.22 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
133109 BRD-K62562723 HT29 0.74 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
133144 BRD-K62562723 JURKAT 0.25 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
133191 BRD-K62562723 MCF10A 0.74 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).