CMap Candidate Details

Structure:
CMap ID: C02231
Pert ID: BRD-A92651262
Compound Name: nalbuphine
Targets: OPRD1; OPRK1; OPRM1
MoA: Opioid receptor agonist; Opioid receptor antagonist
SMILES: O[C@H]1CC[C@@]2(O)[C@H]3Cc4ccc(O)c5OC1[C@]2(CCN3CC1CCC1)c45
InchiKey: NETZHAKZCGBWSS-XDWDPSITSA-N
Compound Aliases: --

Score ID Pert ID Cell Line Pert Dose Pert Time Raw Score (GSE126848) Normalized Score (GSE126848) fdr_q_nlog10 (GSE126848) Raw Score (GSE135251) Normalized Score (GSE135251) fdr_q_nlog10 (GSE135251)
2825 BRD-A92651262 HA1E 10 uM 24 h 0.0 0.0 0.0 0.2 0.71 0.02
3125 BRD-A92651262 HCC515 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
3458 BRD-A92651262 PC3 10 uM 24 h 0.0 0.0 0.0 -0.4 -1.36 2.02
3710 BRD-A92651262 VCAP 10 uM 24 h 0.0 0.0 0.0 -0.29 -0.99 0.51
44268 BRD-A92651262 A375 10 uM 6 h 0.0 0.0 0.0 0.32 1.12 0.76
44499 BRD-A92651262 A549 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
44797 BRD-A92651262 ASC 10 uM 24 h 0.0 0.0 0.0 0.37 1.32 1.59
45116 BRD-A92651262 HEPG2 10 uM 6 h -0.22 -0.93 0.07 0.0 0.0 0.0
45388 BRD-A92651262 HT29 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
45626 BRD-A92651262 MCF??7.00 10 uM 24 h 0.0 0.0 0.0 -0.32 -1.08 0.79
45917 BRD-A92651262 NPC 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
46234 BRD-A92651262 PHH 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
46547 BRD-A92651262 SKB 10 uM 24 h 0.0 0.0 0.0 0.29 1.01 0.46
The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).