CMap Candidate Details

Structure:
CMap ID: C22336
Pert ID: BRD-K62676709
Compound Name: guanethidine
Targets: --
MoA: --
SMILES: NC(=N)NCCN1CCCCCCC1
InchiKey: ACGDKVXYNVEAGU-UHFFFAOYSA-N
Compound Aliases: --

Score ID Pert ID Cell Line Pert Dose Pert Time Raw Score (GSE126848) Normalized Score (GSE126848) fdr_q_nlog10 (GSE126848) Raw Score (GSE135251) Normalized Score (GSE135251) fdr_q_nlog10 (GSE135251)
124960 BRD-K62676709 A549 0.37 uM 24 h 0.0 0.0 0.0 -0.35 -1.19 1.16
124993 BRD-K62676709 HA1E 0.04 uM 24 h -0.22 -0.93 0.07 0.0 0.0 0.0
125020 BRD-K62676709 HELA 3.33 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
125070 BRD-K62676709 MCF10A 1.11 uM 24 h 0.18 0.74 0.0 0.0 0.0 0.0
125105 BRD-K62676709 MDAMB231 1.11 uM 24 h 0.38 1.59 1.52 0.0 0.0 0.0
125152 BRD-K62676709 THP1 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
132974 BRD-K62676709 A375 0.01 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
133038 BRD-K62676709 HEK293 0.74 uM 24 h 0.0 0.0 0.0 -0.28 -0.95 0.41
133110 BRD-K62676709 HT29 0.74 uM 24 h 0.0 0.0 0.0 0.31 1.11 0.72
133145 BRD-K62676709 JURKAT 0.25 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
133218 BRD-K62676709 MCF??7.00 2.22 uM 24 h -0.25 -1.03 0.19 -0.35 -1.18 1.14
133284 BRD-K62676709 PC3 0.01 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
133311 BRD-K62676709 YAPC 2.22 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).