CMap Candidate Details

Structure:
CMap ID: C02235
Pert ID: BRD-A92800748
Compound Name: BRD-A92800748
Targets: --
MoA: --
SMILES: COc1ccc2cc(ccc2c1)-c1nc([nH]c1-c1ccncc1)-c1ccc(cc1)S(C)=O
InchiKey: SINQIEAULQKUPD-UHFFFAOYSA-N
Compound Aliases: tie2-kinase-inhibitor

Score ID Pert ID Cell Line Pert Dose Pert Time Raw Score (GSE126848) Normalized Score (GSE126848) fdr_q_nlog10 (GSE126848) Raw Score (GSE135251) Normalized Score (GSE135251) fdr_q_nlog10 (GSE135251)
94464 BRD-A92800748 A549 10 uM 24 h -0.2 -0.83 0.0 0.0 0.0 0.0
94500 BRD-A92800748 ASC 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
94576 BRD-A92800748 CD34 10 uM 24 h 0.33 1.37 0.97 -0.32 -1.06 0.74
94616 BRD-A92800748 HCC515 0.37 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
94664 BRD-A92800748 HEK293 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
94711 BRD-A92800748 HELA 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
94771 BRD-A92800748 HME1 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
94809 BRD-A92800748 HT29 10 uM 24 h 0.0 0.0 0.0 -0.29 -0.96 0.44
94862 BRD-A92800748 HUVEC 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
94914 BRD-A92800748 JURKAT 0.37 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
94958 BRD-A92800748 MCF10A 1.11 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
94989 BRD-A92800748 MCF??7.00 1.11 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
95040 BRD-A92800748 NEU 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
95098 BRD-A92800748 NPC 10 uM 24 h 0.0 0.0 0.0 0.33 1.18 0.97
95189 BRD-A92800748 SHSY5Y 0.37 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
95224 BRD-A92800748 SKL 1.11 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
95298 BRD-A92800748 THP1 3.33 uM 24 h 0.0 0.0 0.0 -0.42 -1.42 3.38
96634 BRD-A92800748 A375 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
96698 BRD-A92800748 PC3 10 uM 24 h -0.25 -1.05 0.24 0.0 0.0 0.0
The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).