CMap Candidate Details

Structure:
CMap ID: C22360
Pert ID: BRD-K62734952
Compound Name: arglabin
Targets: FNTA; NFKB1
MoA: Farnesyltransferase inhibitor
SMILES: CC1=CC[C@]23O[C@@]2(C)CC[C@@H]2[C@H](OC(=O)C2=C)[C@@H]13
InchiKey: UVJYAKBJSGRTHA-CUZKYEQNSA-N
Compound Aliases: --

Score ID Pert ID Cell Line Pert Dose Pert Time Raw Score (GSE126848) Normalized Score (GSE126848) fdr_q_nlog10 (GSE126848) Raw Score (GSE135251) Normalized Score (GSE135251) fdr_q_nlog10 (GSE135251)
95487 BRD-K62734952 A549 10 uM 24 h 0.0 0.0 0.0 -0.23 -0.77 0.08
95620 BRD-K62734952 U2OS 10 uM 24 h 0.3 1.26 0.57 0.23 0.83 0.12
96908 BRD-K62734952 PC3 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
124933 BRD-K62734952 A375 10 uM 24 h 0.27 1.11 0.25 0.0 0.0 0.0
124994 BRD-K62734952 HA1E 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
125021 BRD-K62734952 HELA 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
125153 BRD-K62734952 THP1 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
125201 BRD-K62734952 YAPC 10 uM 24 h 0.28 1.18 0.4 -0.34 -1.13 0.98
133039 BRD-K62734952 HEK293 2.22 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
133111 BRD-K62734952 HT29 0.08 uM 24 h 0.29 1.22 0.48 0.0 0.0 0.0
133146 BRD-K62734952 JURKAT 0.74 uM 24 h 0.0 0.0 0.0 -0.32 -1.08 0.81
133192 BRD-K62734952 MCF10A 0.25 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
133219 BRD-K62734952 MCF??7.00 2.22 uM 24 h -0.25 -1.04 0.22 0.0 0.0 0.0
133255 BRD-K62734952 MDAMB231 2.22 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).