CMap Candidate Details

Structure:
CMap ID: C22361
Pert ID: BRD-K62736196
Compound Name: guanaben-acetate
Targets: ADRA2A; ADRA2B
MoA: Adrenergic receptor agonist
SMILES: NC(=N)NN=Cc1c(Cl)cccc1Cl
InchiKey: WDZVGELJXXEGPV-YIXHJXPBSA-N
Compound Aliases: --

Score ID Pert ID Cell Line Pert Dose Pert Time Raw Score (GSE126848) Normalized Score (GSE126848) fdr_q_nlog10 (GSE126848) Raw Score (GSE135251) Normalized Score (GSE135251) fdr_q_nlog10 (GSE135251)
5349 BRD-K62736196 HA1E 10 uM 24 h 0.25 1.02 0.13 -0.28 -0.93 0.34
5660 BRD-K62736196 HCC515 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
5938 BRD-K62736196 HEPG2 10 uM 6 h 0.0 0.0 0.0 0.4 1.4 2.18
6043 BRD-K62736196 HT29 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
6207 BRD-K62736196 PC3 10 uM 24 h 0.0 0.0 0.0 -0.34 -1.13 0.99
6395 BRD-K62736196 VCAP 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
39154 BRD-K62736196 A375 10 uM 6 h 0.0 0.0 0.0 0.28 0.98 0.39
39469 BRD-K62736196 A549 10 uM 6 h 0.22 0.93 0.05 0.0 0.0 0.0
39727 BRD-K62736196 ASC 10 uM 24 h 0.19 0.8 0.0 -0.36 -1.21 1.24
40625 BRD-K62736196 MCF??7.00 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
40838 BRD-K62736196 NEU 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
41145 BRD-K62736196 NPC 10 uM 24 h 0.0 0.0 0.0 0.31 1.11 0.73
41483 BRD-K62736196 SKB 10 uM 24 h 0.0 0.0 0.0 -0.29 -0.99 0.51
91017 BRD-K62736196 HUH7 15 uM 72 h 0.0 0.0 0.0 0.0 0.0 0.0
The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).