CMap Candidate Details

Structure:
CMap ID: C22362
Pert ID: BRD-K62737565
Compound Name: gabapentin
Targets: CACNA1B; CACNA2D1; CACNA2D2
MoA: Calcium channel blocker
SMILES: NCC1(CC(O)=O)CCCCC1
InchiKey: UGJMXCAKCUNAIE-UHFFFAOYSA-N
Compound Aliases: --

Score ID Pert ID Cell Line Pert Dose Pert Time Raw Score (GSE126848) Normalized Score (GSE126848) fdr_q_nlog10 (GSE126848) Raw Score (GSE135251) Normalized Score (GSE135251) fdr_q_nlog10 (GSE135251)
91066 BRD-K62737565 HUH7 20 uM 72 h -0.24 -1.02 0.18 0.0 0.0 0.0
124601 BRD-K62737565 A549 1.11 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
124624 BRD-K62737565 HA1E 1.11 uM 24 h 0.0 0.0 0.0 -0.26 -0.89 0.27
124704 BRD-K62737565 HT29 3.33 uM 24 h 0.24 0.99 0.1 0.32 1.12 0.78
124810 BRD-K62737565 MDAMB231 0.125 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
124853 BRD-K62737565 PC3 0.04 uM 24 h 0.27 1.12 0.26 0.0 0.0 0.0
124894 BRD-K62737565 THP1 1.11 uM 24 h 0.0 0.0 0.0 -0.39 -1.31 1.71
132671 BRD-K62737565 A375 0.74 uM 24 h -0.27 -1.12 0.38 -0.23 -0.78 0.09
132767 BRD-K62737565 HEK293 0.03 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
132796 BRD-K62737565 HELA 0.08 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
132843 BRD-K62737565 JURKAT 0.01 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
132881 BRD-K62737565 MCF10A 0.25 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
132909 BRD-K62737565 MCF??7.00 0.25 uM 24 h 0.0 0.0 0.0 0.31 1.11 0.72
132966 BRD-K62737565 YAPC 0.08 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).