CMap Candidate Details

Structure:
CMap ID: C22370
Pert ID: BRD-K62762455
Compound Name: RU-58841
Targets: AR
MoA: Androgen receptor antagonist
SMILES: CC1(C)N(CCCCO)C(=O)N(C1=O)c1ccc(C#N)c(c1)C(F)(F)F
InchiKey: ARBYGDBJECGMGA-UHFFFAOYSA-N
Compound Aliases: --

Score ID Pert ID Cell Line Pert Dose Pert Time Raw Score (GSE126848) Normalized Score (GSE126848) fdr_q_nlog10 (GSE126848) Raw Score (GSE135251) Normalized Score (GSE135251) fdr_q_nlog10 (GSE135251)
124934 BRD-K62762455 A375 0.04 uM 24 h 0.0 0.0 0.0 0.37 1.33 1.71
124961 BRD-K62762455 A549 0.125 uM 24 h -0.2 -0.83 0.0 0.21 0.76 0.05
125022 BRD-K62762455 HELA 1.11 uM 24 h -0.24 -0.99 0.13 0.0 0.0 0.0
125106 BRD-K62762455 MDAMB231 0.04 uM 24 h 0.0 0.0 0.0 -0.25 -0.85 0.19
125154 BRD-K62762455 THP1 10 uM 24 h 0.0 0.0 0.0 0.22 0.78 0.07
125202 BRD-K62762455 YAPC 0.04 uM 24 h 0.24 1.0 0.1 0.3 1.05 0.58
133010 BRD-K62762455 HA1E 0.25 uM 24 h 0.0 0.0 0.0 -0.28 -0.93 0.35
133040 BRD-K62762455 HEK293 0.03 uM 24 h -0.19 -0.81 0.0 -0.24 -0.8 0.12
133112 BRD-K62762455 HT29 0.25 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
133147 BRD-K62762455 JURKAT 2.22 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
133193 BRD-K62762455 MCF10A 0.01 uM 24 h -0.25 -1.04 0.22 -0.18 -0.62 0.0
133220 BRD-K62762455 MCF??7.00 0.25 uM 24 h 0.2 0.85 0.01 0.25 0.87 0.17
133285 BRD-K62762455 PC3 0.01 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).