CMap Candidate Details

Structure:
CMap ID: C02238
Pert ID: BRD-A93000692
Compound Name: ciglitazone
Targets: PPARG
MoA: PPAR receptor agonist
SMILES: CC1(COc2ccc(CC3SC(=O)NC3=O)cc2)CCCCC1
InchiKey: YZFWTZACSRHJQD-UHFFFAOYSA-N
Compound Aliases: --

Score ID Pert ID Cell Line Pert Dose Pert Time Raw Score (GSE126848) Normalized Score (GSE126848) fdr_q_nlog10 (GSE126848) Raw Score (GSE135251) Normalized Score (GSE135251) fdr_q_nlog10 (GSE135251)
3126 BRD-A93000692 HCC515 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
3934 BRD-A93000692 VCAP 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
45117 BRD-A93000692 HEPG2 10 uM 6 h 0.0 0.0 0.0 0.29 1.04 0.54
45755 BRD-A93000692 MCF??7.00 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
46235 BRD-A93000692 PHH 10 uM 24 h -0.18 -0.76 0.0 0.25 0.9 0.22
46548 BRD-A93000692 SKB 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
96099 BRD-A93000692 A549 10 uM 24 h -0.25 -1.03 0.2 -0.24 -0.79 0.11
98788 BRD-A93000692 NPC 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
98983 BRD-A93000692 NEU 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
128423 BRD-A93000692 HEK293 0.04 uM 24 h 0.24 1.0 0.11 0.0 0.0 0.0
128495 BRD-A93000692 HT29 3.33 uM 24 h 0.0 0.0 0.0 -0.17 -0.59 0.0
128533 BRD-A93000692 JURKAT 3.33 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
128586 BRD-A93000692 MCF10A 10 uM 24 h 0.0 0.0 0.0 -0.3 -1.0 0.52
128626 BRD-A93000692 MDAMB231 1.11 uM 24 h 0.0 0.0 0.0 0.27 0.97 0.35
128674 BRD-A93000692 PC3 0.37 uM 24 h 0.0 0.0 0.0 -0.24 -0.82 0.14
128706 BRD-A93000692 THP1 1.11 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
128756 BRD-A93000692 YAPC 1.11 uM 24 h 0.24 1.01 0.12 -0.35 -1.19 1.16
136167 BRD-A93000692 A375 2.22 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
136212 BRD-A93000692 HA1E 0.01 uM 24 h 0.0 0.0 0.0 -0.25 -0.85 0.19
136253 BRD-A93000692 HELA 0.01 uM 24 h 0.24 1.01 0.11 0.29 1.02 0.48
The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).