CMap Candidate Details

Structure:
CMap ID: C22382
Pert ID: BRD-K62792802
Compound Name: LY-83583
Targets: GUCY1A2
MoA: Guanylyl cyclase inhibitor
SMILES: O=C1C=C(Nc2ccccc2)C(=O)c3cccnc13
InchiKey: GXIJYWUWLNHKNW-UHFFFAOYSA-N
Compound Aliases: --

Score ID Pert ID Cell Line Pert Dose Pert Time Raw Score (GSE126848) Normalized Score (GSE126848) fdr_q_nlog10 (GSE126848) Raw Score (GSE135251) Normalized Score (GSE135251) fdr_q_nlog10 (GSE135251)
5221 BRD-K62792802 A375 10 uM 6 h 0.0 0.0 0.0 -0.32 -1.08 0.79
5471 BRD-K62792802 HA1E 10 uM 6 h 0.0 0.0 0.0 -0.26 -0.88 0.25
5661 BRD-K62792802 HCC515 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
5939 BRD-K62792802 HEPG2 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
6044 BRD-K62792802 HT29 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
6109 BRD-K62792802 MCF??7.00 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
6208 BRD-K62792802 PC3 10 uM 24 h 0.0 0.0 0.0 0.32 1.12 0.77
6577 BRD-K62792802 VCAP 10 uM 6 h 0.0 0.0 0.0 0.42 1.49 2.25
The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).