CMap Candidate Details
Structure:
| CMap ID: | C22392 |
| Pert ID: | BRD-K62814476 |
| Compound Name: | BMS-265246 |
| Targets: | CDK2; CDK1 |
| MoA: | CDK inhibitor |
| SMILES: | CCCCOc1c(cnc2[nH]ncc12)C(=O)c1c(F)cc(C)cc1F |
| InchiKey: | SCFMWQIQBVZOQR-UHFFFAOYSA-N |
| Compound Aliases: | -- |
| Score ID | Pert ID | Cell Line | Pert Dose | Pert Time | Raw Score (GSE126848) | Normalized Score (GSE126848) | fdr_q_nlog10 (GSE126848) | Raw Score (GSE135251) | Normalized Score (GSE135251) | fdr_q_nlog10 (GSE135251) |
|---|---|---|---|---|---|---|---|---|---|---|
| 90861 | BRD-K62814476 | MCF10A | 1.11 uM | 24 h | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 |
| 96885 | BRD-K62814476 | A375 | 3.33 uM | 24 h | -0.23 | -0.96 | 0.1 | 0.0 | 0.0 | 0.0 |
| 96963 | BRD-K62814476 | PC3 | 10 uM | 24 h | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 |
| 97327 | BRD-K62814476 | HAP1 | 3.33 uM | 24 h | -0.19 | -0.8 | 0.0 | 0.0 | 0.0 | 0.0 |