CMap Candidate Details

Structure:
CMap ID: C22407
Pert ID: BRD-K62858456
Compound Name: lomerizine
Targets: --
MoA: --
SMILES: COc1ccc(CN2CCN(CC2)C(c2ccc(F)cc2)c2ccc(F)cc2)c(OC)c1OC
InchiKey: JQSAYKKFZOSZGJ-UHFFFAOYSA-N
Compound Aliases: --

Score ID Pert ID Cell Line Pert Dose Pert Time Raw Score (GSE126848) Normalized Score (GSE126848) fdr_q_nlog10 (GSE126848) Raw Score (GSE135251) Normalized Score (GSE135251) fdr_q_nlog10 (GSE135251)
1160 BRD-K62858456 MCF??7.00 10 uM 24 h 0.21 0.88 0.02 0.3 1.05 0.57
1187 BRD-K62858456 PC3 10 uM 24 h -0.24 -1.0 0.15 0.0 0.0 0.0
1259 BRD-K62858456 A549 10 uM 48 h 0.0 0.0 0.0 0.28 1.01 0.44
1336 BRD-K62858456 U2OS 10 uM 24 h -0.27 -1.11 0.37 0.0 0.0 0.0
25402 BRD-K62858456 VCAP 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
91210 BRD-K62858456 HUH7 6.66 uM 72 h 0.0 0.0 0.0 0.0 0.0 0.0
124574 BRD-K62858456 A375 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
124611 BRD-K62858456 HA1E 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
124655 BRD-K62858456 HELA 0.04 uM 24 h -0.2 -0.82 0.0 0.26 0.93 0.28
124687 BRD-K62858456 HT29 0.125 uM 24 h 0.22 0.93 0.05 0.0 0.0 0.0
124720 BRD-K62858456 JURKAT 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
124740 BRD-K62858456 MCF10A 3.33 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
124790 BRD-K62858456 MDAMB231 3.33 uM 24 h 0.29 1.2 0.42 0.0 0.0 0.0
124873 BRD-K62858456 THP1 10 uM 24 h 0.0 0.0 0.0 -0.3 -1.0 0.52
124911 BRD-K62858456 YAPC 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
132747 BRD-K62858456 HEK293 0.03 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).