CMap Candidate Details

Structure:
CMap ID: C02242
Pert ID: BRD-A93206962
Compound Name: L-755507
Targets: ADRB3
MoA: Adrenergic receptor agonist
SMILES: CCCCCCNC(=O)Nc1ccc(cc1)S(=O)(=O)Nc2ccc(CCNCC(O)COc3ccc(O)cc3)cc2
InchiKey: NYYJKMXNVNFOFQ-UHFFFAOYSA-N
Compound Aliases: --

Score ID Pert ID Cell Line Pert Dose Pert Time Raw Score (GSE126848) Normalized Score (GSE126848) fdr_q_nlog10 (GSE126848) Raw Score (GSE135251) Normalized Score (GSE135251) fdr_q_nlog10 (GSE135251)
5420 BRD-A93206962 HA1E 10 uM 6 h 0.0 0.0 0.0 -0.29 -0.97 0.45
5562 BRD-A93206962 HCC515 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
5867 BRD-A93206962 HEPG2 10 uM 6 h 0.0 0.0 0.0 0.2 0.72 0.02
5997 BRD-A93206962 HT29 10 uM 6 h 0.0 0.0 0.0 -0.33 -1.1 0.86
6156 BRD-A93206962 PC3 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
6501 BRD-A93206962 VCAP 10 uM 6 h 0.0 0.0 0.0 0.29 1.04 0.55
37111 BRD-A93206962 A375 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
37260 BRD-A93206962 A549 10 uM 24 h -0.22 -0.9 0.04 0.0 0.0 0.0
37567 BRD-A93206962 ASC 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
38173 BRD-A93206962 MCF??7.00 10 uM 24 h 0.0 0.0 0.0 0.35 1.22 1.15
38406 BRD-A93206962 NPC 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
38673 BRD-A93206962 PHH 10 uM 24 h 0.28 1.18 0.39 0.31 1.11 0.73
38898 BRD-A93206962 SKB 10 uM 24 h 0.0 0.0 0.0 0.22 0.79 0.07
100397 BRD-A93206962 U2OS 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).