CMap Candidate Details

Structure:
CMap ID: C22453
Pert ID: BRD-K62996583
Compound Name: lidoflazine
Targets: --
MoA: --
SMILES: Cc1cccc(C)c1NC(=O)CN1CCN(CCCC(c2ccc(F)cc2)c2ccc(F)cc2)CC1
InchiKey: ZBIAKUMOEKILTF-UHFFFAOYSA-N
Compound Aliases: --

Score ID Pert ID Cell Line Pert Dose Pert Time Raw Score (GSE126848) Normalized Score (GSE126848) fdr_q_nlog10 (GSE126848) Raw Score (GSE135251) Normalized Score (GSE135251) fdr_q_nlog10 (GSE135251)
4128 BRD-K62996583 HA1E 10 uM 24 h -0.26 -1.07 0.27 -0.28 -0.95 0.4
4452 BRD-K62996583 HCC515 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
5100 BRD-K62996583 VCAP 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
39728 BRD-K62996583 ASC 10 uM 24 h 0.0 0.0 0.0 0.25 0.88 0.18
40025 BRD-K62996583 HEPG2 10 uM 6 h 0.0 0.0 0.0 -0.22 -0.75 0.06
40839 BRD-K62996583 NEU 10 uM 24 h 0.0 0.0 0.0 -0.28 -0.93 0.34
41146 BRD-K62996583 NPC 10 uM 24 h -0.29 -1.19 0.55 -0.43 -1.45 15.35
41484 BRD-K62996583 SKB 10 uM 24 h -0.26 -1.07 0.28 -0.29 -0.97 0.46
99314 BRD-K62996583 U2OS 4 uM 6 h 0.0 0.0 0.0 0.32 1.15 0.88
124577 BRD-K62996583 A375 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
124595 BRD-K62996583 A549 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
124658 BRD-K62996583 HELA 10 uM 24 h 0.0 0.0 0.0 -0.35 -1.17 1.11
124691 BRD-K62996583 HT29 10 uM 24 h 0.0 0.0 0.0 0.2 0.71 0.02
124722 BRD-K62996583 JURKAT 0.37 uM 24 h -0.21 -0.86 0.01 0.26 0.93 0.27
124794 BRD-K62996583 MDAMB231 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
124835 BRD-K62996583 PC3 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
124877 BRD-K62996583 THP1 10 uM 24 h -0.23 -0.95 0.09 -0.3 -1.0 0.55
124914 BRD-K62996583 YAPC 10 uM 24 h 0.2 0.85 0.0 0.45 1.59 2.37
132751 BRD-K62996583 HEK293 0.25 uM 24 h 0.0 0.0 0.0 -0.27 -0.9 0.28
132866 BRD-K62996583 MCF10A 0.01 uM 24 h -0.22 -0.92 0.06 -0.43 -1.45 15.35
132897 BRD-K62996583 MCF??7.00 0.25 uM 24 h -0.2 -0.83 0.0 -0.25 -0.85 0.2
The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).