CMap Candidate Details

Structure:
CMap ID: C22485
Pert ID: BRD-K63126190
Compound Name: epinephrine
Targets: ADRA1D; ADRA1B; ADRA1A; ADRA2A; ADRA2B; ADRA2C; ADRB1; ADRB2; ADRB3
MoA: Neurotransmitter; Adrenergic receptor agonist
SMILES: CNC[C@H](O)c1ccc(O)c(O)c1
InchiKey: UCTWMZQNUQWSLP-VIFPVBQESA-N
Compound Aliases: --

Score ID Pert ID Cell Line Pert Dose Pert Time Raw Score (GSE126848) Normalized Score (GSE126848) fdr_q_nlog10 (GSE126848) Raw Score (GSE135251) Normalized Score (GSE135251) fdr_q_nlog10 (GSE135251)
125071 BRD-K63126190 MCF10A 10 uM 24 h -0.32 -1.34 0.98 0.0 0.0 0.0
125107 BRD-K63126190 MDAMB231 1.11 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
125155 BRD-K63126190 THP1 1.11 uM 24 h -0.33 -1.39 1.09 -0.37 -1.24 1.3
125203 BRD-K63126190 YAPC 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
132975 BRD-K63126190 A375 2.22 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
132993 BRD-K63126190 A549 0.03 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
133011 BRD-K63126190 HA1E 0.01 uM 24 h -0.24 -1.01 0.16 0.0 0.0 0.0
133041 BRD-K63126190 HEK293 0.25 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
133086 BRD-K63126190 HELA 0.74 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
133113 BRD-K63126190 HT29 0.08 uM 24 h 0.23 0.97 0.08 0.0 0.0 0.0
133148 BRD-K63126190 JURKAT 0.08 uM 24 h 0.0 0.0 0.0 -0.43 -1.46 15.35
133221 BRD-K63126190 MCF??7.00 0.01 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
133286 BRD-K63126190 PC3 2.22 uM 24 h 0.28 1.18 0.39 0.0 0.0 0.0
The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).