CMap Candidate Details

Structure:
CMap ID: C22491
Pert ID: BRD-K63150726
Compound Name: JTE-907
Targets: CNR2
MoA: Cannabinoid receptor inverse agonist
SMILES: CCCCCOc1c(OC)ccc2cc(C(=O)NCc3ccc4OCOc4c3)c(=O)[nH]c12
InchiKey: GRAJFFFXJYFVOC-UHFFFAOYSA-N
Compound Aliases: --

Score ID Pert ID Cell Line Pert Dose Pert Time Raw Score (GSE126848) Normalized Score (GSE126848) fdr_q_nlog10 (GSE126848) Raw Score (GSE135251) Normalized Score (GSE135251) fdr_q_nlog10 (GSE135251)
1595 BRD-K63150726 HA1E 10 uM 24 h -0.24 -1.02 0.18 0.0 0.0 0.0
1936 BRD-K63150726 HCC515 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
2506 BRD-K63150726 VCAP 10 uM 24 h 0.16 0.66 0.0 0.0 0.0 0.0
42424 BRD-K63150726 ASC 10 uM 24 h 0.0 0.0 0.0 0.25 0.89 0.21
42740 BRD-K63150726 HEPG2 10 uM 6 h -0.25 -1.04 0.22 0.0 0.0 0.0
43339 BRD-K63150726 MCF??7.00 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
43605 BRD-K63150726 NPC 10 uM 24 h 0.0 0.0 0.0 -0.29 -0.98 0.47
43907 BRD-K63150726 PHH 10 uM 24 h -0.2 -0.81 0.0 -0.25 -0.85 0.2
44164 BRD-K63150726 SKB 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
99316 BRD-K63150726 U2OS 10 uM 6 h -0.21 -0.87 0.02 0.25 0.88 0.18
124963 BRD-K63150726 A549 10 uM 24 h 0.0 0.0 0.0 -0.27 -0.9 0.28
125053 BRD-K63150726 HT29 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
125074 BRD-K63150726 MCF10A 3.33 uM 24 h 0.23 0.98 0.08 0.28 1.01 0.44
125109 BRD-K63150726 MDAMB231 10 uM 24 h 0.0 0.0 0.0 0.2 0.7 0.02
125131 BRD-K63150726 PC3 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
125159 BRD-K63150726 THP1 10 uM 24 h 0.0 0.0 0.0 -0.37 -1.26 1.36
132977 BRD-K63150726 A375 0.74 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
133045 BRD-K63150726 HEK293 0.03 uM 24 h 0.0 0.0 0.0 0.3 1.05 0.56
133090 BRD-K63150726 HELA 0.74 uM 24 h 0.23 0.97 0.08 -0.32 -1.06 0.74
133152 BRD-K63150726 JURKAT 0.74 uM 24 h 0.0 0.0 0.0 -0.43 -1.43 15.35
133313 BRD-K63150726 YAPC 0.74 uM 24 h 0.0 0.0 0.0 0.26 0.93 0.27
The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).