CMap Candidate Details

Structure:
CMap ID: C22513
Pert ID: BRD-K63195589
Compound Name: tipifarnib
Targets: --
MoA: --
SMILES: Cn1cncc1[C@](N)(c1ccc(Cl)cc1)c1ccc2n(C)c(=O)cc(-c3cccc(Cl)c3)c2c1
InchiKey: PLHJCIYEEKOWNM-MHZLTWQESA-N
Compound Aliases: --

Score ID Pert ID Cell Line Pert Dose Pert Time Raw Score (GSE126848) Normalized Score (GSE126848) fdr_q_nlog10 (GSE126848) Raw Score (GSE135251) Normalized Score (GSE135251) fdr_q_nlog10 (GSE135251)
9469 BRD-K63195589 AGS 10 uM 6 h 0.0 0.0 0.0 -0.34 -1.16 1.09
9776 BRD-K63195589 H1299 10 uM 6 h 0.22 0.91 0.03 -0.23 -0.79 0.11
9984 BRD-K63195589 HA1E 10 uM 24 h 0.21 0.87 0.01 0.0 0.0 0.0
10235 BRD-K63195589 HCC515 10 uM 24 h 0.0 0.0 0.0 -0.41 -1.36 2.02
10818 BRD-K63195589 HEPG2 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
10994 BRD-K63195589 HT29 10 uM 24 h 0.0 0.0 0.0 0.3 1.07 0.62
11535 BRD-K63195589 NCIH2073 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
11803 BRD-K63195589 NCIH508 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
12355 BRD-K63195589 NOMO1 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
12834 BRD-K63195589 SW480 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
13091 BRD-K63195589 THP1 10 uM 6 h -0.29 -1.22 0.61 0.0 0.0 0.0
13321 BRD-K63195589 U937 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
13491 BRD-K63195589 VCAP 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
95498 BRD-K63195589 A549 10 uM 48 h 0.0 0.0 0.0 0.0 0.0 0.0
95566 BRD-K63195589 MCF??7.00 10 uM 48 h 0.0 0.0 0.0 -0.34 -1.15 1.07
95654 BRD-K63195589 U2OS 10 uM 48 h 0.0 0.0 0.0 -0.27 -0.9 0.27
96042 BRD-K63195589 PHH 1.11 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
96827 BRD-K63195589 A375 3.33 uM 24 h 0.0 0.0 0.0 0.28 1.0 0.43
96904 BRD-K63195589 PC3 10 uM 24 h 0.0 0.0 0.0 -0.31 -1.03 0.63
The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).