CMap Candidate Details

Structure:
CMap ID: C02254
Pert ID: BRD-A93659613
Compound Name: GR-89696
Targets: OPRK1
MoA: Opioid receptor agonist
SMILES: COC(=O)N1CCN(C(CN2CCCC2)C1)C(=O)Cc3ccc(Cl)c(Cl)c3
InchiKey: HJUAKZYKCANOOZ-UHFFFAOYSA-N
Compound Aliases: --

Score ID Pert ID Cell Line Pert Dose Pert Time Raw Score (GSE126848) Normalized Score (GSE126848) fdr_q_nlog10 (GSE126848) Raw Score (GSE135251) Normalized Score (GSE135251) fdr_q_nlog10 (GSE135251)
1522 BRD-A93659613 HA1E 10 uM 24 h -0.23 -0.95 0.09 0.0 0.0 0.0
1855 BRD-A93659613 HCC515 10 uM 24 h -0.2 -0.82 0.0 0.17 0.59 0.0
2289 BRD-A93659613 PC3 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
2624 BRD-A93659613 VCAP 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
39079 BRD-A93659613 A375 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
39418 BRD-A93659613 A549 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
39609 BRD-A93659613 ASC 10 uM 24 h 0.18 0.77 0.0 0.22 0.77 0.06
39929 BRD-A93659613 HEPG2 10 uM 6 h 0.0 0.0 0.0 -0.42 -1.41 2.02
40214 BRD-A93659613 HT29 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
40444 BRD-A93659613 MCF??7.00 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
40733 BRD-A93659613 NEU 10 uM 24 h 0.0 0.0 0.0 -0.36 -1.21 1.24
41035 BRD-A93659613 NPC 10 uM 24 h -0.24 -0.98 0.13 0.34 1.21 1.15
41358 BRD-A93659613 SKB 10 uM 24 h 0.0 0.0 0.0 -0.24 -0.82 0.15
100403 BRD-A93659613 U2OS 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).