CMap Candidate Details

Structure:
CMap ID: C22620
Pert ID: BRD-K63533170
Compound Name: AM-630
Targets: CNR1; CNR2
MoA: Cannabinoid receptor antagonist
SMILES: COc1ccc(cc1)C(=O)c1c(C)n(CCN2CCOCC2)c2cc(I)ccc12
InchiKey: JHOTYHDSLIUKCJ-UHFFFAOYSA-N
Compound Aliases: --

Score ID Pert ID Cell Line Pert Dose Pert Time Raw Score (GSE126848) Normalized Score (GSE126848) fdr_q_nlog10 (GSE126848) Raw Score (GSE135251) Normalized Score (GSE135251) fdr_q_nlog10 (GSE135251)
4129 BRD-K63533170 HA1E 10 uM 24 h 0.0 0.0 0.0 -0.39 -1.33 1.71
4457 BRD-K63533170 HCC515 10 uM 24 h -0.35 -1.45 1.43 -0.45 -1.5 15.35
4702 BRD-K63533170 PC3 10 uM 24 h 0.0 0.0 0.0 -0.26 -0.87 0.22
4947 BRD-K63533170 VCAP 10 uM 24 h 0.21 0.89 0.02 0.0 0.0 0.0
39157 BRD-K63533170 A375 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
39470 BRD-K63533170 A549 10 uM 6 h 0.0 0.0 0.0 -0.32 -1.09 0.83
39732 BRD-K63533170 ASC 10 uM 24 h 0.0 0.0 0.0 -0.38 -1.27 1.43
40029 BRD-K63533170 HEPG2 10 uM 6 h -0.24 -1.0 0.15 0.0 0.0 0.0
40301 BRD-K63533170 HT29 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
40627 BRD-K63533170 MCF??7.00 10 uM 6 h -0.34 -1.42 1.43 0.0 0.0 0.0
41150 BRD-K63533170 NPC 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
41488 BRD-K63533170 SKB 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
99320 BRD-K63533170 U2OS 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).