CMap Candidate Details

Structure:
CMap ID: C02263
Pert ID: BRD-A94276798
Compound Name: talinolol
Targets: ADRB1
MoA: Adrenergic receptor antagonist
SMILES: CC(C)(C)NCC(O)COc1ccc(NC(=O)NC2CCCCC2)cc1
InchiKey: MXFWWQICDIZSOA-UHFFFAOYSA-N
Compound Aliases: --

Score ID Pert ID Cell Line Pert Dose Pert Time Raw Score (GSE126848) Normalized Score (GSE126848) fdr_q_nlog10 (GSE126848) Raw Score (GSE135251) Normalized Score (GSE135251) fdr_q_nlog10 (GSE135251)
128381 BRD-A94276798 A549 0.04 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
128436 BRD-A94276798 HEK293 0.37 uM 24 h 0.0 0.0 0.0 0.3 1.07 0.64
128477 BRD-A94276798 HELA 3.33 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
128546 BRD-A94276798 JURKAT 3.33 uM 24 h 0.24 1.01 0.12 -0.37 -1.25 1.35
128593 BRD-A94276798 MCF10A 0.37 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
128608 BRD-A94276798 MCF??7.00 0.125 uM 24 h 0.0 0.0 0.0 0.3 1.06 0.59
128638 BRD-A94276798 MDAMB231 0.125 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
128680 BRD-A94276798 PC3 10 uM 24 h -0.19 -0.81 0.0 0.0 0.0 0.0
128718 BRD-A94276798 THP1 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
128765 BRD-A94276798 YAPC 10 uM 24 h 0.21 0.87 0.01 0.0 0.0 0.0
136178 BRD-A94276798 A375 0.03 uM 24 h 0.0 0.0 0.0 -0.38 -1.28 1.45
136223 BRD-A94276798 HA1E 0.01 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
136288 BRD-A94276798 HT29 0.08 uM 24 h 0.0 0.0 0.0 0.27 0.97 0.35
The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).