CMap Candidate Details

Structure:
CMap ID: C22642
Pert ID: BRD-K63606607
Compound Name: bufalin
Targets: ATP1A1
MoA: ATPase inhibitor
SMILES: C[C@@]12CC[C@H]3[C@@H](CC[C@@H]4C[C@@H](O)CC[C@@]43C)[C@@]2(O)CC[C@@H]1c5ccc(=O)oc5
InchiKey: QEEBRPGZBVVINN-BMPKRDENSA-N
Compound Aliases: --

Score ID Pert ID Cell Line Pert Dose Pert Time Raw Score (GSE126848) Normalized Score (GSE126848) fdr_q_nlog10 (GSE126848) Raw Score (GSE135251) Normalized Score (GSE135251) fdr_q_nlog10 (GSE135251)
4130 BRD-K63606607 HA1E 10 uM 24 h 0.0 0.0 0.0 -0.39 -1.3 1.58
4458 BRD-K63606607 HCC515 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
4816 BRD-K63606607 PC3 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
5105 BRD-K63606607 VCAP 10 uM 6 h 0.0 0.0 0.0 0.33 1.15 0.9
44427 BRD-K63606607 A375 10 uM 6 h 0.0 0.0 0.0 -0.45 -1.51 15.35
44602 BRD-K63606607 A549 10 uM 24 h 0.0 0.0 0.0 -0.57 -1.92 15.65
45001 BRD-K63606607 ASC 10 uM 24 h 0.26 1.09 0.22 -0.35 -1.18 1.15
45292 BRD-K63606607 HEPG2 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
45555 BRD-K63606607 HT29 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
45837 BRD-K63606607 MCF??7.00 10 uM 6 h 0.23 0.95 0.07 -0.43 -1.46 15.35
46114 BRD-K63606607 NPC 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
46429 BRD-K63606607 PHH 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
46754 BRD-K63606607 SKB 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
99321 BRD-K63606607 U2OS 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).