CMap Candidate Details

Structure:
CMap ID: C22663
Pert ID: BRD-K63675182
Compound Name: triflupromazine
Targets: DRD2; HTR2B
MoA: Dopamine receptor antagonist
SMILES: CN(C)CCCN1c2ccccc2Sc2ccc(cc12)C(F)(F)F
InchiKey: XSCGXQMFQXDFCW-UHFFFAOYSA-N
Compound Aliases: --

Score ID Pert ID Cell Line Pert Dose Pert Time Raw Score (GSE126848) Normalized Score (GSE126848) fdr_q_nlog10 (GSE126848) Raw Score (GSE135251) Normalized Score (GSE135251) fdr_q_nlog10 (GSE135251)
5662 BRD-K63675182 HCC515 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
5940 BRD-K63675182 HEPG2 10 uM 6 h 0.0 0.0 0.0 0.26 0.92 0.24
6578 BRD-K63675182 VCAP 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
39733 BRD-K63675182 ASC 10 uM 24 h -0.26 -1.07 0.28 0.25 0.89 0.21
40491 BRD-K63675182 MCF??7.00 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
41151 BRD-K63675182 NPC 10 uM 24 h 0.0 0.0 0.0 -0.33 -1.12 0.95
41489 BRD-K63675182 SKB 10 uM 24 h 0.17 0.71 0.0 0.37 1.32 1.59
124576 BRD-K63675182 A375 10 uM 24 h -0.24 -1.01 0.17 0.0 0.0 0.0
124614 BRD-K63675182 HA1E 10 uM 24 h 0.18 0.75 0.0 0.26 0.91 0.23
124657 BRD-K63675182 HELA 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
124690 BRD-K63675182 HT29 10 uM 24 h 0.0 0.0 0.0 0.31 1.09 0.67
124743 BRD-K63675182 MCF10A 0.125 uM 24 h -0.23 -0.96 0.09 -0.4 -1.36 2.02
124793 BRD-K63675182 MDAMB231 10 uM 24 h 0.28 1.18 0.38 0.0 0.0 0.0
124834 BRD-K63675182 PC3 10 uM 24 h 0.0 0.0 0.0 -0.41 -1.38 2.02
124876 BRD-K63675182 THP1 10 uM 24 h 0.22 0.91 0.04 -0.33 -1.11 0.9
124913 BRD-K63675182 YAPC 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
132686 BRD-K63675182 A549 0.03 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
132750 BRD-K63675182 HEK293 0.01 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
132832 BRD-K63675182 JURKAT 0.03 uM 24 h -0.27 -1.13 0.4 0.0 0.0 0.0
The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).