CMap Candidate Details

Structure:
CMap ID: C22671
Pert ID: BRD-K63712959
Compound Name: temoporfin
Targets: --
MoA: --
SMILES: Oc1cccc(c1)-c1c2CCc(n2)c(-c2cccc(O)c2)c2ccc([nH]2)c(-c2cccc(O)c2)c2ccc(n2)c(-c2cccc(O)c2)c2ccc1[nH]2
InchiKey: LYPFDBRUNKHDGX-UHFFFAOYSA-N
Compound Aliases: --

Score ID Pert ID Cell Line Pert Dose Pert Time Raw Score (GSE126848) Normalized Score (GSE126848) fdr_q_nlog10 (GSE126848) Raw Score (GSE135251) Normalized Score (GSE135251) fdr_q_nlog10 (GSE135251)
121717 BRD-K63712959 A375 10 uM 24 h 0.19 0.79 0.0 0.0 0.0 0.0
121753 BRD-K63712959 HELA 10 uM 24 h 0.0 0.0 0.0 0.33 1.18 1.0
121781 BRD-K63712959 HT29 10 uM 24 h 0.0 0.0 0.0 0.28 0.99 0.4
121832 BRD-K63712959 PC3 10 uM 24 h -0.2 -0.83 0.0 0.0 0.0 0.0
121862 BRD-K63712959 YAPC 10 uM 24 h 0.0 0.0 0.0 0.29 1.02 0.49
129778 BRD-K63712959 HA1E 2.22 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
129809 BRD-K63712959 HEK293 0.01 uM 24 h -0.27 -1.12 0.38 0.24 0.83 0.12
129935 BRD-K63712959 MCF10A 0.01 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
129986 BRD-K63712959 MCF??7.00 2.22 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
130020 BRD-K63712959 MDAMB231 0.03 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
130093 BRD-K63712959 THP1 0.03 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).