CMap Candidate Details

Structure:
CMap ID: C02268
Pert ID: BRD-A94413429
Compound Name: NTNCB
Targets: NPY5R
MoA: Neuropeptide receptor antagonist
SMILES: [O-][N+](=O)c1ccccc1S(=O)(=O)NCC2CCC(CNCC3CCc4ccccc4C3)CC2
InchiKey: ISSSVYKMIIAPTH-UHFFFAOYSA-N
Compound Aliases: --

Score ID Pert ID Cell Line Pert Dose Pert Time Raw Score (GSE126848) Normalized Score (GSE126848) fdr_q_nlog10 (GSE126848) Raw Score (GSE135251) Normalized Score (GSE135251) fdr_q_nlog10 (GSE135251)
1523 BRD-A94413429 HA1E 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
2059 BRD-A94413429 HCC515 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
2290 BRD-A94413429 PC3 10 uM 24 h 0.2 0.84 0.0 0.42 1.5 2.27
2775 BRD-A94413429 VCAP 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
39080 BRD-A94413429 A375 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
39291 BRD-A94413429 A549 10 uM 24 h 0.0 0.0 0.0 0.29 1.04 0.55
39610 BRD-A94413429 ASC 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
39930 BRD-A94413429 HEPG2 10 uM 6 h 0.0 0.0 0.0 0.34 1.2 1.06
40215 BRD-A94413429 HT29 10 uM 6 h -0.21 -0.86 0.01 0.0 0.0 0.0
40445 BRD-A94413429 MCF??7.00 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
40734 BRD-A94413429 NEU 10 uM 24 h 0.0 0.0 0.0 -0.29 -0.98 0.47
41036 BRD-A94413429 NPC 10 uM 24 h 0.0 0.0 0.0 -0.28 -0.94 0.38
41359 BRD-A94413429 SKB 10 uM 24 h 0.0 0.0 0.0 0.37 1.32 1.71
100406 BRD-A94413429 U2OS 10 uM 6 h 0.0 0.0 0.0 0.28 1.0 0.42
136418 BRD-A94413429 SHSY5Y 10 uM 24 h 0.0 0.0 0.0 0.36 1.28 1.37
The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).