CMap Candidate Details

Structure:
CMap ID: C22728
Pert ID: BRD-K63874012
Compound Name: thioperamide
Targets: HRH3; HRH4
MoA: Histamine receptor antagonist
SMILES: S=C(NC1CCCCC1)N1CCC(CC1)c1c[nH]cn1
InchiKey: QKDDJDBFONZGBW-UHFFFAOYSA-N
Compound Aliases: --

Score ID Pert ID Cell Line Pert Dose Pert Time Raw Score (GSE126848) Normalized Score (GSE126848) fdr_q_nlog10 (GSE126848) Raw Score (GSE135251) Normalized Score (GSE135251) fdr_q_nlog10 (GSE135251)
1596 BRD-K63874012 HA1E 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
1937 BRD-K63874012 HCC515 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
2404 BRD-K63874012 PC3 10 uM 6 h 0.0 0.0 0.0 0.23 0.81 0.08
2553 BRD-K63874012 VCAP 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
41813 BRD-K63874012 A375 10 uM 6 h 0.0 0.0 0.0 0.33 1.17 0.93
42121 BRD-K63874012 A549 10 uM 6 h -0.25 -1.06 0.26 -0.22 -0.74 0.06
42425 BRD-K63874012 ASC 10 uM 24 h -0.27 -1.12 0.39 0.0 0.0 0.0
42741 BRD-K63874012 HEPG2 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
43040 BRD-K63874012 HT29 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
43908 BRD-K63874012 PHH 10 uM 24 h 0.25 1.03 0.13 -0.3 -1.0 0.54
52180 BRD-K63874012 MCF??7.00 10 uM 6 h 0.0 0.0 0.0 -0.28 -0.95 0.41
98157 BRD-K63874012 NPC 10 uM 24 h 0.0 0.0 0.0 0.29 1.04 0.53
98414 BRD-K63874012 NEU 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).