CMap Candidate Details

Structure:
CMap ID: C22764
Pert ID: BRD-K63954456
Compound Name: BRD-K63954456
Targets: MIF
MoA: TNF production inhibitor
SMILES: COc1cc(cc(Br)c1OCC(=O)O)c2nc3ccccc3s2
InchiKey: VKGGBLHFFRIHKZ-UHFFFAOYSA-N
Compound Aliases: --

Score ID Pert ID Cell Line Pert Dose Pert Time Raw Score (GSE126848) Normalized Score (GSE126848) fdr_q_nlog10 (GSE126848) Raw Score (GSE135251) Normalized Score (GSE135251) fdr_q_nlog10 (GSE135251)
26145 BRD-K63954456 A549 10 uM 6 h 0.17 0.71 0.0 0.0 0.0 0.0
26417 BRD-K63954456 ASC 10 uM 24 h 0.0 0.0 0.0 0.31 1.1 0.7
26742 BRD-K63954456 HA1E 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
27047 BRD-K63954456 HCC515 10 uM 6 h 0.0 0.0 0.0 -0.38 -1.27 1.43
27355 BRD-K63954456 HT29 10 uM 6 h 0.0 0.0 0.0 0.33 1.16 0.9
27736 BRD-K63954456 MCF??7.00 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
27986 BRD-K63954456 NEU 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
28300 BRD-K63954456 NPC 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
28671 BRD-K63954456 PC3 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
28932 BRD-K63954456 PHH 10 uM 24 h 0.0 0.0 0.0 -0.23 -0.77 0.08
29267 BRD-K63954456 SKB 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
29660 BRD-K63954456 VCAP 10 uM 6 h 0.31 1.28 0.61 0.31 1.11 0.71
The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).