CMap Candidate Details

Structure:
CMap ID: C02278
Pert ID: BRD-A94624445
Compound Name: bucladesine
Targets: PRKACA
MoA: CAMP stimulant; Adenosine receptor agonist
SMILES: CCCC(=O)Nc1ncnc2n(cnc12)[C@@H]1O[C@@H]2COP(O)(=O)O[C@H]2[C@H]1OC(=O)CCC
InchiKey: CJGYSWNGNKCJSB-YVLZZHOMSA-N
Compound Aliases: --

Score ID Pert ID Cell Line Pert Dose Pert Time Raw Score (GSE126848) Normalized Score (GSE126848) fdr_q_nlog10 (GSE126848) Raw Score (GSE135251) Normalized Score (GSE135251) fdr_q_nlog10 (GSE135251)
1714 BRD-A94624445 HA1E 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
1856 BRD-A94624445 HCC515 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
2211 BRD-A94624445 PC3 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
2700 BRD-A94624445 VCAP 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
41692 BRD-A94624445 A375 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
41892 BRD-A94624445 A549 10 uM 24 h 0.0 0.0 0.0 -0.22 -0.73 0.04
42244 BRD-A94624445 ASC 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
42582 BRD-A94624445 HEPG2 10 uM 6 h 0.0 0.0 0.0 -0.32 -1.09 0.83
42889 BRD-A94624445 HT29 10 uM 6 h 0.0 0.0 0.0 -0.34 -1.15 1.06
43275 BRD-A94624445 MCF??7.00 10 uM 6 h 0.0 0.0 0.0 -0.3 -1.01 0.57
43442 BRD-A94624445 NPC 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
43749 BRD-A94624445 PHH 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
44034 BRD-A94624445 SKB 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
100408 BRD-A94624445 U2OS 10 uM 6 h 0.23 0.95 0.06 0.0 0.0 0.0
The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).