CMap Candidate Details

Structure:
CMap ID: C22787
Pert ID: BRD-K64034691
Compound Name: acalabrutinib
Targets: --
MoA: --
SMILES: CC#CC(=O)N1CCC[C@H]1c1nc(-c2ccc(cc2)C(=O)Nc2ccccn2)c2c(N)nccn12
InchiKey: WDENQIQQYWYTPO-IBGZPJMESA-N
Compound Aliases: --

Score ID Pert ID Cell Line Pert Dose Pert Time Raw Score (GSE126848) Normalized Score (GSE126848) fdr_q_nlog10 (GSE126848) Raw Score (GSE135251) Normalized Score (GSE135251) fdr_q_nlog10 (GSE135251)
87332 BRD-K64034691 BJAB 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
87376 BRD-K64034691 HBL1 10 uM 24 h 0.0 0.0 0.0 0.26 0.92 0.24
87425 BRD-K64034691 K562 0.125 uM 24 h 0.0 0.0 0.0 -0.27 -0.89 0.27
87473 BRD-K64034691 KMS34 0.01 uM 24 h 0.0 0.0 0.0 -0.28 -0.95 0.41
87490 BRD-K64034691 MINO 2.5 uM 24 h 0.0 0.0 0.0 0.22 0.8 0.08
87577 BRD-K64034691 NALM6 2.5 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
87628 BRD-K64034691 OCILY10 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
87677 BRD-K64034691 OCILY19 0.01 uM 24 h -0.18 -0.73 0.0 0.32 1.14 0.85
87729 BRD-K64034691 OCILY3 0.04 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
87776 BRD-K64034691 SKMEL5 0.01 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
87796 BRD-K64034691 THP1 0.01 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
87839 BRD-K64034691 TMD8 0.01 uM 24 h 0.0 0.0 0.0 0.32 1.13 0.82
95533 BRD-K64034691 A549 10 uM 6 h 0.0 0.0 0.0 0.23 0.82 0.1
95578 BRD-K64034691 MCF??7.00 10 uM 48 h 0.0 0.0 0.0 0.0 0.0 0.0
95618 BRD-K64034691 U2OS 1.11 uM 24 h 0.22 0.92 0.04 0.0 0.0 0.0
The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).