CMap Candidate Details

Structure:
CMap ID: C02280
Pert ID: BRD-A94669766
Compound Name: naringenin
Targets: CYP19A1; ESR2
MoA: TRPV antagonist; Aromatase inhibitor
SMILES: Oc1ccc(cc1)C2CC(=O)c3c(O)cc(O)cc3O2
InchiKey: FTVWIRXFELQLPI-UHFFFAOYSA-N
Compound Aliases: --

Score ID Pert ID Cell Line Pert Dose Pert Time Raw Score (GSE126848) Normalized Score (GSE126848) fdr_q_nlog10 (GSE126848) Raw Score (GSE135251) Normalized Score (GSE135251) fdr_q_nlog10 (GSE135251)
5291 BRD-A94669766 HA1E 10 uM 24 h 0.0 0.0 0.0 0.39 1.39 2.17
5745 BRD-A94669766 HCC515 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
5998 BRD-A94669766 HT29 10 uM 6 h -0.25 -1.06 0.26 0.0 0.0 0.0
6157 BRD-A94669766 PC3 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
6397 BRD-A94669766 VCAP 10 uM 24 h 0.19 0.78 0.0 -0.26 -0.88 0.25
39081 BRD-A94669766 A375 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
39419 BRD-A94669766 A549 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
39611 BRD-A94669766 ASC 10 uM 24 h 0.25 1.05 0.17 -0.2 -0.67 0.02
39931 BRD-A94669766 HEPG2 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
40446 BRD-A94669766 MCF??7.00 10 uM 24 h 0.0 0.0 0.0 0.31 1.11 0.72
40735 BRD-A94669766 NEU 10 uM 24 h 0.0 0.0 0.0 -0.31 -1.03 0.65
41037 BRD-A94669766 NPC 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
41360 BRD-A94669766 SKB 10 uM 24 h -0.23 -0.94 0.08 0.0 0.0 0.0
100409 BRD-A94669766 U2OS 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).