CMap Candidate Details

Structure:
CMap ID: C02287
Pert ID: BRD-A94793051
Compound Name: gestrinone
Targets: ESR1; AR; PGR
MoA: Progesterone receptor antagonist
SMILES: CC[C@]1(O)CCC2[C@@H]3CCC4=CC(=O)CCC4=C3C=C[C@@]12CC
InchiKey: OXHNQTSIKGHVBH-WVVQBRDUSA-N
Compound Aliases: --

Score ID Pert ID Cell Line Pert Dose Pert Time Raw Score (GSE126848) Normalized Score (GSE126848) fdr_q_nlog10 (GSE126848) Raw Score (GSE135251) Normalized Score (GSE135251) fdr_q_nlog10 (GSE135251)
49790 BRD-A94793051 A375 10 uM 6 h 0.0 0.0 0.0 -0.26 -0.87 0.23
50132 BRD-A94793051 HA1E 10 uM 6 h -0.33 -1.38 1.09 -0.34 -1.14 1.03
50320 BRD-A94793051 HCC515 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
50485 BRD-A94793051 HT29 10 uM 6 h 0.24 1.01 0.11 0.0 0.0 0.0
50645 BRD-A94793051 MCF??7.00 10 uM 24 h 0.0 0.0 0.0 -0.28 -0.95 0.39
50896 BRD-A94793051 PC3 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
51114 BRD-A94793051 VCAP 10 uM 6 h 0.0 0.0 0.0 -0.29 -0.98 0.48
96100 BRD-A94793051 A549 10 uM 24 h -0.24 -1.01 0.16 -0.38 -1.29 1.55
The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).