CMap Candidate Details

Structure:
CMap ID: C22928
Pert ID: BRD-K64504314
Compound Name: dienogest
Targets: PGR
MoA: Progesterone receptor agonist
SMILES: C[C@@]12CCC3=C4CCC(=O)C=C4CC[C@H]3[C@@H]1CC[C@@]2(O)CC#N
InchiKey: AZFLJNIPTRTECV-IYWMVGAKSA-N
Compound Aliases: --

Score ID Pert ID Cell Line Pert Dose Pert Time Raw Score (GSE126848) Normalized Score (GSE126848) fdr_q_nlog10 (GSE126848) Raw Score (GSE135251) Normalized Score (GSE135251) fdr_q_nlog10 (GSE135251)
124662 BRD-K64504314 HELA 10 uM 24 h 0.23 0.95 0.06 0.24 0.86 0.15
124695 BRD-K64504314 HT29 3.33 uM 24 h -0.3 -1.24 0.67 0.0 0.0 0.0
124841 BRD-K64504314 PC3 3.33 uM 24 h 0.0 0.0 0.0 -0.32 -1.07 0.76
124883 BRD-K64504314 THP1 0.37 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
132663 BRD-K64504314 A375 2.22 uM 24 h -0.32 -1.32 0.85 0.0 0.0 0.0
132691 BRD-K64504314 A549 0.74 uM 24 h -0.25 -1.03 0.2 0.0 0.0 0.0
132722 BRD-K64504314 HA1E 2.22 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
132758 BRD-K64504314 HEK293 0.01 uM 24 h 0.0 0.0 0.0 0.38 1.36 1.72
132837 BRD-K64504314 JURKAT 0.03 uM 24 h 0.0 0.0 0.0 -0.48 -1.6 15.65
132873 BRD-K64504314 MCF10A 0.03 uM 24 h 0.0 0.0 0.0 -0.31 -1.04 0.68
132901 BRD-K64504314 MCF??7.00 2.22 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
132917 BRD-K64504314 MDAMB231 0.74 uM 24 h 0.25 1.05 0.17 -0.21 -0.71 0.03
132954 BRD-K64504314 YAPC 0.74 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).