CMap Candidate Details

Structure:
CMap ID: C22983
Pert ID: BRD-K64634304
Compound Name: tretinoin
Targets: RARA; RARB; RARG; RORB
MoA: Retinoid receptor ligand; Retinoid receptor agonist
SMILES: CC(=CCO)C=CC=C(C)C=CC1=C(C)CCCC1(C)C
InchiKey: FPIPGXGPPPQFEQ-UHFFFAOYSA-N
Compound Aliases: --

Score ID Pert ID Cell Line Pert Dose Pert Time Raw Score (GSE126848) Normalized Score (GSE126848) fdr_q_nlog10 (GSE126848) Raw Score (GSE135251) Normalized Score (GSE135251) fdr_q_nlog10 (GSE135251)
9471 BRD-K64634304 AGS 40 uM 6 h 0.0 0.0 0.0 0.31 1.09 0.67
9777 BRD-K64634304 H1299 40 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
9895 BRD-K64634304 HA1E 40 uM 24 h 0.0 0.0 0.0 -0.38 -1.28 1.45
10139 BRD-K64634304 HCC515 40 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
10559 BRD-K64634304 HCT116 40 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
10819 BRD-K64634304 HEPG2 40 uM 6 h -0.27 -1.11 0.37 0.0 0.0 0.0
10995 BRD-K64634304 HT29 40 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
11151 BRD-K64634304 MCF??7.00 40 uM 24 h 0.0 0.0 0.0 -0.26 -0.89 0.26
11805 BRD-K64634304 NCIH508 40 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
12098 BRD-K64634304 NCIH596 40 uM 6 h -0.23 -0.96 0.1 0.0 0.0 0.0
12457 BRD-K64634304 PC3 40 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
12836 BRD-K64634304 SW480 40 uM 6 h 0.0 0.0 0.0 -0.22 -0.74 0.05
13322 BRD-K64634304 U937 40 uM 6 h -0.29 -1.22 0.61 0.26 0.92 0.25
13652 BRD-K64634304 VCAP 40 uM 6 h 0.0 0.0 0.0 -0.28 -0.94 0.38
95768 BRD-K64634304 A375 3.33 uM 6 h 0.0 0.0 0.0 -0.27 -0.9 0.28
95810 BRD-K64634304 NPC 3.33 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
95837 BRD-K64634304 A549 3.33 uM 6 h -0.23 -0.96 0.1 0.31 1.1 0.69
95925 BRD-K64634304 YAPC 3.33 uM 6 h -0.29 -1.22 0.61 0.0 0.0 0.0
97480 BRD-K64634304 NKDBA 40 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).