CMap Candidate Details

Structure:
CMap ID: C23025
Pert ID: BRD-K64746805
Compound Name: MBCQ
Targets: PDE5A
MoA: Phosphodiesterase inhibitor
SMILES: Clc1ccc2ncnc(NCc3ccc4OCOc4c3)c2c1
InchiKey: CNODHOSDWZLJGA-UHFFFAOYSA-N
Compound Aliases: mbcq

Score ID Pert ID Cell Line Pert Dose Pert Time Raw Score (GSE126848) Normalized Score (GSE126848) fdr_q_nlog10 (GSE126848) Raw Score (GSE135251) Normalized Score (GSE135251) fdr_q_nlog10 (GSE135251)
6902 BRD-K64746805 A375 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
7189 BRD-K64746805 A549 10 uM 6 h -0.2 -0.85 0.01 0.19 0.68 0.01
7351 BRD-K64746805 HA1E 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
7705 BRD-K64746805 HCC515 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
7908 BRD-K64746805 HT29 10 uM 24 h 0.0 0.0 0.0 -0.35 -1.19 1.15
8194 BRD-K64746805 MCF??7.00 10 uM 6 h 0.0 0.0 0.0 -0.25 -0.85 0.19
8403 BRD-K64746805 PC3 10 uM 24 h 0.0 0.0 0.0 -0.28 -0.95 0.41
8841 BRD-K64746805 VCAP 10 uM 6 h 0.0 0.0 0.0 0.27 0.96 0.34
The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).