CMap Candidate Details

Structure:
CMap ID: C23090
Pert ID: BRD-K64935403
Compound Name: ebelactone-b
Targets: PNLIP
MoA: Lipase inhibitor
SMILES: CC[C@@H](C)[C@@H](O)[C@H](C)C(=O)[C@H](C)C=C(/C)C[C@H](C)[C@H]1OC(=O)[C@H]1CC
InchiKey: UNBMQQNYLCPCHS-MGTGEOTMSA-N
Compound Aliases: --

Score ID Pert ID Cell Line Pert Dose Pert Time Raw Score (GSE126848) Normalized Score (GSE126848) fdr_q_nlog10 (GSE126848) Raw Score (GSE135251) Normalized Score (GSE135251) fdr_q_nlog10 (GSE135251)
33664 BRD-K64935403 A375 10 uM 6 h 0.0 0.0 0.0 -0.27 -0.9 0.28
33821 BRD-K64935403 A549 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
34147 BRD-K64935403 ASC 10 uM 24 h 0.0 0.0 0.0 -0.3 -1.02 0.61
34397 BRD-K64935403 HA1E 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
34658 BRD-K64935403 HCC515 10 uM 6 h 0.16 0.68 0.0 0.0 0.0 0.0
34926 BRD-K64935403 HEPG2 10 uM 6 h 0.0 0.0 0.0 0.31 1.1 0.69
35176 BRD-K64935403 HT29 10 uM 6 h -0.32 -1.33 0.9 -0.38 -1.28 1.45
35334 BRD-K64935403 MCF??7.00 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
35598 BRD-K64935403 NEU 10 uM 24 h 0.0 0.0 0.0 -0.31 -1.04 0.67
35818 BRD-K64935403 NPC 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
35977 BRD-K64935403 PC3 10 uM 24 h 0.0 0.0 0.0 -0.35 -1.18 1.14
36310 BRD-K64935403 PHH 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
36608 BRD-K64935403 SKB 10 uM 24 h 0.22 0.92 0.04 0.0 0.0 0.0
36848 BRD-K64935403 VCAP 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).