CMap Candidate Details

Structure:
CMap ID: C23148
Pert ID: BRD-K65146499
Compound Name: nabumetone
Targets: PTGS2
MoA: Cyclooxygenase inhibitor
SMILES: COc1ccc2cc(CCC(C)=O)ccc2c1
InchiKey: BLXXJMDCKKHMKV-UHFFFAOYSA-N
Compound Aliases: --

Score ID Pert ID Cell Line Pert Dose Pert Time Raw Score (GSE126848) Normalized Score (GSE126848) fdr_q_nlog10 (GSE126848) Raw Score (GSE135251) Normalized Score (GSE135251) fdr_q_nlog10 (GSE135251)
6903 BRD-K65146499 A375 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
7190 BRD-K65146499 A549 10 uM 6 h -0.27 -1.13 0.4 0.0 0.0 0.0
7479 BRD-K65146499 HA1E 10 uM 6 h 0.0 0.0 0.0 0.19 0.69 0.01
7707 BRD-K65146499 HCC515 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
7909 BRD-K65146499 HT29 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
8145 BRD-K65146499 MCF??7.00 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
8719 BRD-K65146499 VCAP 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
91256 BRD-K65146499 HUH7 15 uM 72 h 0.0 0.0 0.0 0.0 0.0 0.0
96398 BRD-K65146499 PC3 1.11 uM 24 h -0.27 -1.11 0.37 0.0 0.0 0.0
99340 BRD-K65146499 U2OS 8 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).