CMap Candidate Details

Structure:
CMap ID: C23161
Pert ID: BRD-K65182930
Compound Name: NVP-AUY922
Targets: HSP90AA1; HSP90AB1
MoA: HSP inhibitor
SMILES: CCNC(=O)C1=C(C(=C2C=C(C(=CC2=O)O)C(C)C)ON1)C3=CC=C(C=C3)CN4CCOCC4
InchiKey: SWDZPNJZKUGIIH-UHFFFAOYSA-N
Compound Aliases: --

Score ID Pert ID Cell Line Pert Dose Pert Time Raw Score (GSE126848) Normalized Score (GSE126848) fdr_q_nlog10 (GSE126848) Raw Score (GSE135251) Normalized Score (GSE135251) fdr_q_nlog10 (GSE135251)
91992 BRD-K65182930 A375 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
92040 BRD-K65182930 BT20 10 uM 3 h 0.0 0.0 0.0 0.0 0.0 0.0
92068 BRD-K65182930 HA1E 0.37 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
92101 BRD-K65182930 HCC515 10 uM 24 h 0.0 0.0 0.0 0.27 0.96 0.33
92159 BRD-K65182930 HS578T 1.11 uM 3 h 0.27 1.12 0.26 -0.26 -0.89 0.27
92189 BRD-K65182930 HT29 3.33 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
92216 BRD-K65182930 MCF10A 0.37 uM 24 h -0.29 -1.22 0.61 0.3 1.05 0.57
92255 BRD-K65182930 MCF??7.00 3.33 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
92290 BRD-K65182930 MDAMB231 0.37 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
92340 BRD-K65182930 PC3 0.12 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
92389 BRD-K65182930 SKBR3 0.04 uM 3 h 0.0 0.0 0.0 0.19 0.69 0.01
The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).