CMap Candidate Details

Structure:
CMap ID: C02318
Pert ID: BRD-A96060515
Compound Name: ipratropium
Targets: CHRM1; CHRM2; CHRM3; CHRM4
MoA: Acetylcholine receptor antagonist
SMILES: CC(C)[N+]1(C)C2CC[C@H]1C[C@H](C2)OC(=O)C(CO)c1ccccc1
InchiKey: OEXHQOGQTVQTAT-QQLIVEQCSA-N
Compound Aliases: --

Score ID Pert ID Cell Line Pert Dose Pert Time Raw Score (GSE126848) Normalized Score (GSE126848) fdr_q_nlog10 (GSE126848) Raw Score (GSE135251) Normalized Score (GSE135251) fdr_q_nlog10 (GSE135251)
128393 BRD-A96060515 A549 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
128451 BRD-A96060515 HEK293 10 uM 24 h 0.0 0.0 0.0 -0.36 -1.23 1.25
128561 BRD-A96060515 JURKAT 1.11 uM 24 h 0.0 0.0 0.0 -0.26 -0.88 0.24
128600 BRD-A96060515 MCF10A 3.33 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
128653 BRD-A96060515 MDAMB231 3.33 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
128733 BRD-A96060515 THP1 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
136190 BRD-A96060515 A375 0.03 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
136235 BRD-A96060515 HA1E 0.01 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
136270 BRD-A96060515 HELA 0.25 uM 24 h 0.24 0.98 0.09 0.0 0.0 0.0
136296 BRD-A96060515 HT29 0.25 uM 24 h 0.0 0.0 0.0 -0.29 -0.96 0.43
136349 BRD-A96060515 MCF??7.00 0.03 uM 24 h 0.0 0.0 0.0 0.24 0.86 0.16
136370 BRD-A96060515 PC3 0.25 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
136388 BRD-A96060515 YAPC 2.22 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).