CMap Candidate Details
Structure:
| CMap ID: | C02319 |
| Pert ID: | BRD-A96107863 |
| Compound Name: | nisoldipine |
| Targets: | CACNA1C; CACNA1D; CACNA1S |
| MoA: | Calcium channel blocker |
| SMILES: | COC(=O)C1C(C(=C(C)N=C1C)C(=O)OCC(C)C)c2ccccc2[N+](=O)[O-] |
| InchiKey: | CMRUBVBRILWITQ-UHFFFAOYSA-N |
| Compound Aliases: | -- |
| Score ID | Pert ID | Cell Line | Pert Dose | Pert Time | Raw Score (GSE126848) | Normalized Score (GSE126848) | fdr_q_nlog10 (GSE126848) | Raw Score (GSE135251) | Normalized Score (GSE135251) | fdr_q_nlog10 (GSE135251) |
|---|---|---|---|---|---|---|---|---|---|---|
| 24402 | BRD-A96107863 | A375 | 10 uM | 6 h | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 |
| 24649 | BRD-A96107863 | A549 | 10 uM | 6 h | -0.25 | -1.05 | 0.23 | 0.0 | 0.0 | 0.0 |
| 24738 | BRD-A96107863 | HA1E | 10 uM | 6 h | 0.0 | 0.0 | 0.0 | -0.27 | -0.9 | 0.29 |
| 24997 | BRD-A96107863 | MCF??7.00 | 10 uM | 24 h | 0.0 | 0.0 | 0.0 | 0.24 | 0.85 | 0.14 |
| 25226 | BRD-A96107863 | PC3 | 10 uM | 6 h | -0.25 | -1.04 | 0.21 | 0.29 | 1.01 | 0.45 |
| 25313 | BRD-A96107863 | VCAP | 10 uM | 24 h | 0.19 | 0.79 | 0.0 | -0.25 | -0.83 | 0.17 |