CMap Candidate Details

Structure:
CMap ID: C23201
Pert ID: BRD-K65342895
Compound Name: BRD-K65342895
Targets: --
MoA: --
SMILES: COCCOC(=O)N1C(=O)[C@]2([C@@H]([C@@H]3N([C@@H]2c4ccccc4OCCO)[C@H]([C@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N7CCN(CC7)c8ncccn8)c9cc(C#CCC(C(=O)OC)C(=O)OC)ccc19
InchiKey: NMHFAXRTWCWMAY-NPTJWLTHSA-N
Compound Aliases: --

Score ID Pert ID Cell Line Pert Dose Pert Time Raw Score (GSE126848) Normalized Score (GSE126848) fdr_q_nlog10 (GSE126848) Raw Score (GSE135251) Normalized Score (GSE135251) fdr_q_nlog10 (GSE135251)
29913 BRD-K65342895 A375 10 uM 6 h -0.26 -1.08 0.3 -0.22 -0.75 0.06
30095 BRD-K65342895 A549 10 uM 24 h 0.0 0.0 0.0 -0.28 -0.94 0.39
30516 BRD-K65342895 ASC 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
30808 BRD-K65342895 HA1E 10 uM 6 h 0.28 1.16 0.34 0.0 0.0 0.0
31102 BRD-K65342895 HCC515 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
31412 BRD-K65342895 HEPG2 10 uM 6 h -0.23 -0.94 0.08 0.0 0.0 0.0
31684 BRD-K65342895 HT29 10 uM 6 h -0.26 -1.09 0.33 -0.29 -0.96 0.44
31907 BRD-K65342895 MCF??7.00 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
32216 BRD-K65342895 NEU 10 uM 24 h -0.29 -1.19 0.55 -0.34 -1.13 1.0
32493 BRD-K65342895 NPC 10 uM 24 h 0.19 0.8 0.0 -0.27 -0.91 0.31
32811 BRD-K65342895 PC3 10 uM 6 h -0.24 -0.99 0.13 0.0 0.0 0.0
33099 BRD-K65342895 SKB 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
33490 BRD-K65342895 VCAP 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).