CMap Candidate Details

Structure:
CMap ID: C02323
Pert ID: BRD-A96292436
Compound Name: eflornithine
Targets: ODC1
MoA: Ornithine decarboxylase inhibitor
SMILES: NCCCC(N)(C(F)F)C(O)=O
InchiKey: VLCYCQAOQCDTCN-UHFFFAOYSA-N
Compound Aliases: --

Score ID Pert ID Cell Line Pert Dose Pert Time Raw Score (GSE126848) Normalized Score (GSE126848) fdr_q_nlog10 (GSE126848) Raw Score (GSE135251) Normalized Score (GSE135251) fdr_q_nlog10 (GSE135251)
128394 BRD-A96292436 A549 0.04 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
128452 BRD-A96292436 HEK293 3.33 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
128562 BRD-A96292436 JURKAT 0.04 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
128601 BRD-A96292436 MCF10A 0.37 uM 24 h 0.0 0.0 0.0 0.21 0.75 0.04
128610 BRD-A96292436 MCF??7.00 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
128654 BRD-A96292436 MDAMB231 0.04 uM 24 h 0.0 0.0 0.0 -0.27 -0.9 0.29
128734 BRD-A96292436 THP1 1.11 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
128777 BRD-A96292436 YAPC 3.33 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
136191 BRD-A96292436 A375 0.03 uM 24 h -0.2 -0.85 0.01 0.0 0.0 0.0
136236 BRD-A96292436 HA1E 0.03 uM 24 h -0.2 -0.82 0.0 0.25 0.87 0.18
136271 BRD-A96292436 HELA 0.25 uM 24 h 0.27 1.12 0.26 0.0 0.0 0.0
136297 BRD-A96292436 HT29 0.08 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
136371 BRD-A96292436 PC3 0.03 uM 24 h 0.22 0.93 0.05 -0.28 -0.93 0.35
The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).