CMap Candidate Details

Structure:
CMap ID: C23261
Pert ID: BRD-K65503129
Compound Name: CCT-018159
Targets: HSP90AA1
MoA: HSP inhibitor
SMILES: CCc1cc(-c2n[nH]c(C)c2-c2ccc3OCCOc3c2)c(O)cc1O
InchiKey: OWPMENVYXDJDOW-UHFFFAOYSA-N
Compound Aliases: HSP-90-INHIBITOR

Score ID Pert ID Cell Line Pert Dose Pert Time Raw Score (GSE126848) Normalized Score (GSE126848) fdr_q_nlog10 (GSE126848) Raw Score (GSE135251) Normalized Score (GSE135251) fdr_q_nlog10 (GSE135251)
4232 BRD-K65503129 HA1E 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
4460 BRD-K65503129 HCC515 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
4704 BRD-K65503129 PC3 10 uM 24 h -0.23 -0.95 0.08 0.0 0.0 0.0
5106 BRD-K65503129 VCAP 10 uM 6 h 0.0 0.0 0.0 -0.31 -1.05 0.7
44429 BRD-K65503129 A375 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
44605 BRD-K65503129 A549 10 uM 24 h 0.0 0.0 0.0 0.38 1.34 1.72
45004 BRD-K65503129 ASC 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
45295 BRD-K65503129 HEPG2 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
45558 BRD-K65503129 HT29 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
45839 BRD-K65503129 MCF??7.00 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
46117 BRD-K65503129 NPC 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
46432 BRD-K65503129 PHH 10 uM 24 h -0.31 -1.3 0.82 -0.42 -1.42 2.02
46757 BRD-K65503129 SKB 10 uM 24 h 0.0 0.0 0.0 -0.35 -1.16 1.11
99342 BRD-K65503129 U2OS 10 uM 6 h -0.25 -1.05 0.23 0.0 0.0 0.0
The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).