CMap Candidate Details

Structure:
CMap ID: C02339
Pert ID: BRD-A96882008
Compound Name: L-732138
Targets: TACR1
MoA: Tachykinin antagonist
SMILES: CC(=O)NC(Cc1c[nH]c2ccccc12)C(=O)OCc3cc(cc(c3)C(F)(F)F)C(F)(F)F
InchiKey: BYYQYXVAWXAYQC-UHFFFAOYSA-N
Compound Aliases: --

Score ID Pert ID Cell Line Pert Dose Pert Time Raw Score (GSE126848) Normalized Score (GSE126848) fdr_q_nlog10 (GSE126848) Raw Score (GSE135251) Normalized Score (GSE135251) fdr_q_nlog10 (GSE135251)
1716 BRD-A96882008 HA1E 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
2065 BRD-A96882008 HCC515 10 uM 6 h 0.0 0.0 0.0 -0.32 -1.07 0.75
2359 BRD-A96882008 PC3 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
2777 BRD-A96882008 VCAP 10 uM 6 h 0.0 0.0 0.0 0.29 1.01 0.46
39083 BRD-A96882008 A375 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
39292 BRD-A96882008 A549 10 uM 24 h 0.0 0.0 0.0 -0.32 -1.08 0.8
39613 BRD-A96882008 ASC 10 uM 24 h 0.0 0.0 0.0 -0.33 -1.12 0.96
39934 BRD-A96882008 HEPG2 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
40217 BRD-A96882008 HT29 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
40585 BRD-A96882008 MCF??7.00 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
40738 BRD-A96882008 NEU 10 uM 24 h 0.27 1.12 0.27 0.0 0.0 0.0
41040 BRD-A96882008 NPC 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
41363 BRD-A96882008 SKB 10 uM 24 h 0.0 0.0 0.0 -0.3 -1.0 0.55
100421 BRD-A96882008 U2OS 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).