CMap Candidate Details

Structure:
CMap ID: C23406
Pert ID: BRD-K65992024
Compound Name: pirenoxine
Targets: --
MoA: --
SMILES: OC(=O)c1cc(O)c2c3nc4ccccc4oc3cc(=O)c2n1
InchiKey: OKPNYGAWTYOBFZ-UHFFFAOYSA-N
Compound Aliases: --

Score ID Pert ID Cell Line Pert Dose Pert Time Raw Score (GSE126848) Normalized Score (GSE126848) fdr_q_nlog10 (GSE126848) Raw Score (GSE135251) Normalized Score (GSE135251) fdr_q_nlog10 (GSE135251)
124581 BRD-K65992024 A375 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
124730 BRD-K65992024 JURKAT 3.33 uM 24 h -0.23 -0.98 0.12 0.29 1.04 0.56
124765 BRD-K65992024 MCF??7.00 1.11 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
124846 BRD-K65992024 PC3 3.33 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
124888 BRD-K65992024 THP1 1.11 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
132695 BRD-K65992024 A549 0.25 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
132725 BRD-K65992024 HA1E 0.74 uM 24 h 0.0 0.0 0.0 0.22 0.79 0.08
132761 BRD-K65992024 HEK293 2.22 uM 24 h 0.0 0.0 0.0 -0.3 -1.0 0.52
132792 BRD-K65992024 HELA 0.25 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
132814 BRD-K65992024 HT29 0.25 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
132877 BRD-K65992024 MCF10A 0.25 uM 24 h -0.35 -1.44 1.43 0.0 0.0 0.0
132919 BRD-K65992024 MDAMB231 0.74 uM 24 h 0.0 0.0 0.0 0.2 0.72 0.03
132959 BRD-K65992024 YAPC 2.22 uM 24 h -0.28 -1.16 0.47 0.0 0.0 0.0
The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).