CMap Candidate Details
Structure:
| CMap ID: | C23423 |
| Pert ID: | BRD-K66043364 |
| Compound Name: | noscapine |
| Targets: | SIGMAR1 |
| MoA: | Tubulin inhibitor; Bradykinin receptor antagonist |
| SMILES: | COc1ccc2[C@@H](OC(=O)c2c1OC)[C@H]1N(C)CCc2cc3OCOc3c(OC)c12 |
| InchiKey: | AKNNEGZIBPJZJG-ZENAZSQFSA-N |
| Compound Aliases: | -- |
| Score ID | Pert ID | Cell Line | Pert Dose | Pert Time | Raw Score (GSE126848) | Normalized Score (GSE126848) | fdr_q_nlog10 (GSE126848) | Raw Score (GSE135251) | Normalized Score (GSE135251) | fdr_q_nlog10 (GSE135251) |
|---|---|---|---|---|---|---|---|---|---|---|
| 49874 | BRD-K66043364 | A375 | 10 uM | 6 h | 0.0 | 0.0 | 0.0 | 0.24 | 0.87 | 0.17 |
| 50036 | BRD-K66043364 | A549 | 10 uM | 6 h | -0.27 | -1.11 | 0.38 | -0.26 | -0.89 | 0.26 |
| 50218 | BRD-K66043364 | HA1E | 10 uM | 6 h | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 |
| 50568 | BRD-K66043364 | HT29 | 10 uM | 6 h | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 |
| 50773 | BRD-K66043364 | MCF??7.00 | 10 uM | 6 h | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 |
| 50857 | BRD-K66043364 | PC3 | 10 uM | 24 h | -0.2 | -0.85 | 0.01 | -0.25 | -0.85 | 0.2 |
| 51167 | BRD-K66043364 | VCAP | 10 uM | 6 h | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 |