CMap Candidate Details

Structure:
CMap ID: C23461
Pert ID: BRD-K66206289
Compound Name: lobeline
Targets: SLC18A2
MoA: Acetylcholine receptor antagonist
SMILES: CN1[C@H](C[C@H](O)c2ccccc2)CCC[C@@H]1CC(=O)c1ccccc1
InchiKey: MXYUKLILVYORSK-HBMCJLEFSA-N
Compound Aliases: --

Score ID Pert ID Cell Line Pert Dose Pert Time Raw Score (GSE126848) Normalized Score (GSE126848) fdr_q_nlog10 (GSE126848) Raw Score (GSE135251) Normalized Score (GSE135251) fdr_q_nlog10 (GSE135251)
24468 BRD-K66206289 A375 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
24692 BRD-K66206289 A549 10 uM 6 h 0.0 0.0 0.0 0.25 0.89 0.21
24800 BRD-K66206289 HA1E 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
24935 BRD-K66206289 HT29 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
25105 BRD-K66206289 MCF??7.00 10 uM 6 h 0.32 1.34 0.89 0.39 1.37 1.97
25179 BRD-K66206289 PC3 10 uM 24 h -0.3 -1.24 0.64 0.34 1.21 1.15
25405 BRD-K66206289 VCAP 10 uM 24 h 0.3 1.25 0.53 -0.33 -1.1 0.86
99348 BRD-K66206289 U2OS 6.66 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).