CMap Candidate Details

Structure:
CMap ID: C02351
Pert ID: BRD-A97701745
Compound Name: pindolol
Targets: ADRB1; ADRB2; HTR1A
MoA: Adrenergic receptor antagonist
SMILES: CC(C)NCC(O)COc1cccc2[nH]ccc12
InchiKey: JZQKKSLKJUAGIC-UHFFFAOYSA-N
Compound Aliases: --

Score ID Pert ID Cell Line Pert Dose Pert Time Raw Score (GSE126848) Normalized Score (GSE126848) fdr_q_nlog10 (GSE126848) Raw Score (GSE135251) Normalized Score (GSE135251) fdr_q_nlog10 (GSE135251)
5292 BRD-A97701745 HA1E 10 uM 24 h 0.0 0.0 0.0 -0.24 -0.81 0.12
5747 BRD-A97701745 HCC515 10 uM 6 h -0.19 -0.78 0.0 0.31 1.1 0.68
5871 BRD-A97701745 HEPG2 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
6506 BRD-A97701745 VCAP 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
37571 BRD-A97701745 ASC 10 uM 24 h 0.0 0.0 0.0 0.29 1.03 0.52
38410 BRD-A97701745 NPC 10 uM 24 h 0.0 0.0 0.0 -0.3 -1.02 0.59
38900 BRD-A97701745 SKB 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
91062 BRD-A97701745 HUH7 12.5 uM 72 h 0.0 0.0 0.0 0.0 0.0 0.0
99935 BRD-A97701745 U2OS 10 uM 6 h -0.2 -0.83 0.0 0.0 0.0 0.0
127334 BRD-A97701745 A375 0.04 uM 24 h 0.0 0.0 0.0 0.25 0.89 0.2
127379 BRD-A97701745 A549 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
127482 BRD-A97701745 HT29 3.33 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
127494 BRD-A97701745 JURKAT 1.11 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
127588 BRD-A97701745 PC3 3.33 uM 24 h 0.24 0.99 0.09 0.0 0.0 0.0
127664 BRD-A97701745 YAPC 3.33 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
135356 BRD-A97701745 HELA 0.08 uM 24 h 0.0 0.0 0.0 0.32 1.13 0.83
135426 BRD-A97701745 MCF10A 0.03 uM 24 h 0.0 0.0 0.0 -0.29 -0.96 0.44
135460 BRD-A97701745 MCF??7.00 0.25 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
135489 BRD-A97701745 THP1 2.22 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).